Oh yeah, definitely a problem with GTR2 or my PC not your software, didn't mean to imply that, just wondered if anyone had come across this before.
Anyway, I had a few more tries and actually got the setting to stick, but I have no idea how, I did not do anything different to all my other tries that I am aware of

other than keep the file open in an editor whilst running GTR2.

Works fine now.
Cheers.
Oh and just as a suggestion ( I dont think it already does it) but would it be possible to enable the various sims to be launched from within Simdash, like you can in the Logitech Profiler etc. Would mean a slightly simpler procedure to get up and racing.